Melissa L. Fishel : rechercher sur Z-Library

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1

Role of glutathione and nucleotide excision repair in modulation of cisplatin activity withO6-benzylguanine

Melissa L. Fishel, Michael P. Gamcsik, Shannon M. Delaney, Eleanor G. Zuhowski, Veronica M. Maher, Theodore Karrison, Robert C. Moschel, Merrill J. Egorin, M. Eileen Dolan

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 399 KB

english, 2005

2

Implication of p53 in base excision DNA repair: in vivo evidence

Seo, Young R, Fishel, Melissa L, Amundson, Sally, Kelley, Mark R, Smith, Martin L

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 311 KB

english, 2002

3

Role of GADD34 in modulation of cisplatin cytotoxicity

Melissa L. Fishel, Cara A. Rabik, Wasim K. Bleibel, Xinmin Li, Robert C. Moschel, M. Eileen Dolan

Journal:

Biochemical Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 348 KB

english, 2006

4

Medulloblastoma Can Be Initiated by Deletion of Patched in Lineage-Restricted Progenitors or Stem Cells

Zeng-Jie Yang, Tammy Ellis, Shirley L. Markant, Tracy-Ann Read, Jessica D. Kessler, Melissa Bourboulas, Ulrich Schüller, Robert Machold, Gord Fishell, David H. Rowitch, Brandon J. Wainwright, Robert J

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 2.32 MB

english, 2008

5

Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth

Melissa L. Fishel, Ying He, April M. Reed, Helen Chin-Sinex, Gary D. Hutchins, Marc S. Mendonca, Mark R. Kelley

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1005 KB

english, 2008

6

Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity

Courtney M. Tate, Melissa L. Fishel, Julianne L. Holleran, Merrill J. Egorin, David G. Skalnik

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2009

7

Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: Use of APE1 small molecule inhibitors to delineate APE1 functions

Yanlin Jiang, Chunlu Guo, Melissa L. Fishel, Zheng-Yu Wang, Michael R. Vasko, Mark R. Kelley

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 974 KB

english, 2009

8

Inhibition of the redox function of APE1/Ref-1 in myeloid leukemia cell lines results in a hypersensitive response to retinoic acid-induced differentiation and apoptosis

Melissa L. Fishel, E. Scott Colvin, Meihua Luo, Mark R. Kelley, Kent A. Robertson

Journal:

Experimental Hematology

Année:

2010

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2010

9

DNA repair in neurons: So if they don’t divide what's to repair?

Melissa L. Fishel, Michael R. Vasko, Mark R. Kelley

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Année:

2007

Langue:

english

Fichier:

PDF, 347 KB

english, 2007

10

The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target

Melissa L. Fishel, Mark R. Kelley

Journal:

Molecular Aspects of Medicine

Année:

2007

Langue:

english

Fichier:

PDF, 261 KB

english, 2007

11

Reduced Expression of DNA Repair and Redox Signaling Protein APE1/Ref-1 Impairs Human Pancreatic Cancer Cell Survival, Proliferation, and Cell Cycle Progression

Jiang, Yanlin, Zhou, Shaoyu, Sandusky, George E., Kelley, Mark R., Fishel, Melissa L.

Journal:

Cancer Investigation

Année:

2010

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2010

12

991 APE1/REF-1 REGULATES SURVIVIN-MEDIATED DRUG RESISTANCE IN PROSTATE CANCER CELLS

McIlwain, David, Fishel, Melissa, Wang, Liang, Snider, Brandy, Zhang, Jian-Ting, Kelley, Mark, Jerde, Travis

Journal:

The Journal of Urology

Année:

2013

Langue:

english

Fichier:

PDF, 60 KB

english, 2013

13

Selective ALDH3A1 Inhibition by Benzimidazole Analogues Increase Mafosfamide Sensitivity in Cancer Cells

Parajuli, Bibek, Fishel, Melissa L., Hurley, Thomas D.

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 3.92 MB

english, 2014

14

Going Ape as an Approach to Cancer Therapeutics

Bapat, Aditi, Fishel, Melissa L., Kelley, Mark R.

Journal:

Antioxidants & Redox Signaling

Année:

2009

Langue:

english

Fichier:

PDF, 700 KB

english, 2009

15

Role of the Multifunctional DNA Repair and Redox Signaling Protein Ape1/Ref-1 in Cancer and Endothelial Cells: Small-Molecule Inhibition of the Redox Function of Ape1

Luo, Meihua, Delaplane, Sarah, Jiang, Aihua, Reed, April, He, Ying, Fishel, Melissa, Nyland, Rodney L., Borch, Richard F., Qiao, Xiaoxi, Georgiadis, Millie M., Kelley, Mark R.

Journal:

Antioxidants & Redox Signaling

Année:

2008

Langue:

english

Fichier:

PDF, 515 KB

english, 2008

16

Development of Selective Inhibitors for Human Aldehyde Dehydrogenase 3A1 (ALDH3A1) for the Enhancement of Cyclophosphamide Cytotoxicity

Parajuli, Bibek, Georgiadis, Taxiarchis M., Fishel, Melissa L., Hurley, Thomas D.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.99 MB

english, 2014

17

Targeting DNA repair pathways for cancer treatment: what’s new?

Kelley, Mark R, Logsdon, Derek, Fishel, Melissa L

Journal:

Future Oncology

Année:

2014

Langue:

english

Fichier:

PDF, 2.23 MB

english, 2014

18

Apurinic/Apyrimidinic Endonuclease/Redox Factor-1 (APE1/Ref-1) Redox Function Negatively Regulates NRF2

Fishel, Melissa L., Wu, Xue, Devlin, Cecilia M., Logsdon, Derek P., Jiang, Yanlin, Luo, Meihua, He, Ying, Yu, Zhangsheng, Tong, Yan, Lipking, Kelsey P., Maitra, Anirban, Rajeshkumar, N. V., Scandura,

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2015

19

Longitudinal Bioluminescence Imaging of Primary Versus Abdominal Metastatic Tumor Growth in Orthotopic Pancreatic Tumor Models in NSG Mice

Shannon, Harlan E., Fishel, Melissa L., Xie, Jingwu, Gu, Dongsheng, McCarthy, Brian P., Riley, Amanda A., Sinn, Anthony L., Silver, Jayne M., Peterman, Kacie, Kelley, Mark R., Hanenberg, Helmut, Korc,

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 11.12 MB

english, 2015

20

Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation

Reed, April M, Fishel, Melissa L, Kelley, Mark R

Journal:

Future Oncology

Année:

2009

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2009

21

DNA Repair Proteins as Molecular Targets for Cancer Therapeutics

Kelley, Mark, Fishel, Melissa

Journal:

Anti-Cancer Agents in Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 300 KB

english, 2008

22

STAT3 in the Systemic Inflammation of Cancer Cachexia

Zimmers, Teresa A., Fishel, Melissa L., Bonetto, Andrea

Journal:

Seminars in Cell & Developmental Biology

Année:

2016

Langue:

english

Fichier:

PDF, 926 KB

english, 2016

23

Tissue Transglutaminase Activates Cancer-Associated Fibroblasts and Contributes to Gemcitabine Resistance in Pancreatic Cancer

Lee, Jiyoon, Yakubov, Bakhtiyor, Ivan, Cristina, Jones, David R., Caperell-Grant, Andrea, Fishel, Melissa, Cardenas, Horacio, Matei, Daniela

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2016

24

Ref-1/APE1 as Transcriptional Regulator and Novel Therapeutic Target in Pediatric T-cell Leukemia

Ding, Jixin, Fishel, Melissa L., Reed, April M., McAdams, Erin, Czader, Magdalena, Cardoso, Angelo A., Kelley, Mark R.

Journal:

Molecular Cancer Therapeutics

Année:

2017

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2017

25

Exploiting the Ref-1-APE1 node in cancer signaling and other diseases: from bench to clinic

Shah, Fenil, Logsdon, Derek, Messmann, Richard A., Fehrenbacher, Jill C., Fishel, Melissa L., Kelley, Mark R.

Journal:

npj Precision Oncology

Année:

2017

Langue:

english

Fichier:

PDF, 2.25 MB

english, 2017

26

APE1/Ref-1 knockdown in pancreatic ductal adenocarcinoma: Characterizing gene expression changes and identifying novel pathways using single-cell RNA sequencing

Shah, Fenil, Goossens, Emery, Atallah, Nadia M., Grimard, Michelle, Kelley, Mark R., Fishel, Melissa L.

Journal:

Molecular Oncology

Année:

2017

Langue:

english

Fichier:

PDF, 9.53 MB

english, 2017

27

PTEN-Dependent Stabilization of MTSS1 Inhibits Metastatic Phenotype in Pancreatic Ductal Adenocarcinoma

Zeleniak, Ann E., Huang, Wei, Fishel, Melissa L., Hill, Reginald

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2018

28

Presence of stromal cells in a bioengineered tumor microenvironment alters glioblastoma migration and response to STAT3 inhibition

Herrera-Perez, R. Marisol, Voytik-Harbin, Sherry L., Sarkaria, Jann N., Pollok, Karen E., Fishel, Melissa L., Rickus, Jenna L., Ulasov, Ilya

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 4.03 MB

english, 2018

29

Ref-1/APE1 inhibition with novel small molecules blocks ocular neovascularization

Sardar Pasha, Sheik Pran Babu, Sishtla, Kamakshi, Sulaiman, Rania S, Park, Bomina, Shetty, Trupti, Shah, Fenil, Fishel, Melissa L, Wikel, James H, Kelley, Mark R, Corson, Timothy W.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Année:

2018

Langue:

english

Fichier:

PDF, 3.88 MB

english, 2018

30

Development of a Novel 3D Tumor-tissue Invasion Model for High-throughput, High-content Phenotypic Drug Screening

Puls, T. J., Tan, Xiaohong, Husain, Mahera, Whittington, Catherine F., Fishel, Melissa L., Voytik-Harbin, Sherry L.

Journal:

Scientific Reports

Année:

2018

Langue:

english

Fichier:

PDF, 5.00 MB

english, 2018

31

Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival

Logsdon, Derek P., Shah, Fenil, Carta, Fabrizio, Supuran, Claudiu T., Kamocka, Malgorzata, Jacobsen, Max H., Sandusky, George E., Kelley, Mark R., Fishel, Melissa L.

Journal:

Scientific Reports

Année:

2018

Langue:

english

Fichier:

PDF, 4.04 MB

english, 2018

32

APE1/Ref-1Role in Redox Signaling: Translational Applications of Targeting the Redox Function of the DNA Repair/Redox Protein APE1/Ref-1

R. Kelley, Mark, M. Georgiadis, Millie, L. Fishel, Melissa

Journal:

Current Molecular Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 10.19 MB

english, 2012

33

Non-Canonical Wnt-Signaling through Ryk Regulates the Generation of Somatostatin- and Parvalbumin-Expressing Cortical Interneurons

McKenzie, Melissa G., Cobbs, Lucy V., Dummer, Patrick D., Petros, Timothy J., Halford, Michael M., Stacker, Steven, Zou, Yimin, Fishell, Gord J., Au, Edmund

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 4.06 MB

english, 2019

34

APE1/Ref-1 redox-specific inhibition decreases survivin protein levels and induces cell cycle arrest in prostate cancer cells

McIlwain, David W., Fishel, Melissa L., Boos, Alexander, Kelley, Mark R., Jerde, Travis J.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 6.33 MB

english, 2018

35

LTMG: a novel statistical modeling of transcriptional expression states in single-cell RNA-Seq data

Wan, Changlin, Chang, Wennan, Zhang, Yu, Shah, Fenil, Lu, Xiaoyu, Zang, Yong, Zhang, Anru, Cao, Sha, Fishel, Melissa L, Ma, Qin, Zhang, Chi

Journal:

Nucleic Acids Research

Année:

2019

Langue:

english

Fichier:

PDF, 2.41 MB

english, 2019

36

Preserving inhibition during developmental hearing loss rescues auditory learning and perception

Mowery, Todd M., Caras, Melissa L., Hassan, Syeda I., Wang, Derek J., Dimidschstein, Jordane, Fishell, Gord, Sanes, Dan H.

Journal:

Journal of Neuroscience

Année:

2019

Langue:

english

Fichier:

PDF, 9.50 MB

english, 2019

37

Antitumor Activity and Mechanistic Characterization of APE1/Ref-1 Inhibitors in Bladder Cancer

Fishel, Melissa L., Xia, Hanyu, McGeown, Jack, McIlwain, David W., Elbanna, May, Craft, Ariel A., Kaimakliotis, Hristos Z., Sandusky, George E., Zhang, Chi, Pili, Roberto, Kelley, Mark R., Jerde, Trav

Journal:

Molecular Cancer Therapeutics

Année:

2019

Langue:

english

Fichier:

PDF, 19.59 MB

english, 2019

38

Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data

Xu, David, Zhou, Donghui, Bum-Erdene, Khuchtumur, Bailey, Barbara J, Sishtla, Kamakshi, Liu, Sheng, Wan, Jun, Aryal, Uma K., Lee, Jonathan A, Wells, Clark D, Fishel, Melissa L., Corson, Timothy W, Pol

Journal:

ACS Chemical Biology

Année:

2020

Langue:

english

Fichier:

PDF, 3.38 MB

english, 2020

39

Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination Immunotherapy

Principe, Daniel R, Narbutis, Matthew, Kumar, Sandeep, Park, Alex, Viswakarma, Navin, Dorman, Matthew J, Kamath, Suneel D, Grippo, Paul J, Fishel, Melissa L, Hwang, Rosa F., Thummuri, Dinesh, Underwoo

Journal:

Cancer Research

Année:

2020

Fichier:

PDF, 11.22 MB

2020

40

The multifunctional APE1 DNA repairâredox signaling protein as a drug target in human disease

Caston, Rachel A., Gampala, Silpa, Armstrong, Lee, Messmann, Richard A., Fishel, Melissa L., Kelley, Mark R.

Journal:

Drug Discovery Today

Année:

2020

Fichier:

PDF, 1.05 MB

2020